AU - Singhai, Abhishek AU - Alam, Ansar TI - A study to assess the pattern of drug resistance and its causes among patients registered as retreatment cases of Tuberculosis in a tertiary care center of central India PT - ORIG DP - 2015 Jan 1 TA - Sifa Medical Journal PG - 11-14 VI - 2 IP - 1 4099- https://www.imjsu.org/article.asp?issn=2148-7731;year=2015;volume=2;issue=1;spage=11;epage=14;aulast=Singhai;type=0 4100- https://www.imjsu.org/article.asp?issn=2148-7731;year=2015;volume=2;issue=1;spage=11;epage=14;aulast=Singhai AB - Context: Tuberculosis is a major public health priority in the world with 8-10 million new cases added every year. Aims: To obtain information about drug resistance pattern of patients registered as re-treatment cases and its causes along with source of previous drug exposure. Settings and Design: This is a prospective study done at a tertiary care center. Materials and Methods: A total of 100 patients of re-treatment cases who gave oral informed consent were registered as subjects. Results: Drug resistance was identified as 25% mono drug and 22% multidrug resistance among retreatment cases. Isoniazid (25%) was the most common drug against which drug resistance was identified. Conclusions: Multidrug resistance is a significant health problem. Majority of these patients were drug defaulters. Our study identifies drug intolerance, ignorance about advised treatment, early symptomatic relief as the predominant causes of defaulting.