RT - Journal TY - JOUR A1 - Turan, Guluzar A1 - Yavuz, Melike A1 - Gur, Esra A1 - Tatar, Sumeyra A1 - Hepyilmaz, Irem A1 - Ergene, Ulku T1 - Cesarean section and ovarian cystectomy in the patient with factor XI deficiency YR - 2014/5/1 JF - Sifa Medical Journal JO - Sifa Med J SP - 21 OP - 23 VO - 1 IS - 2 UL - https://www.imjsu.org/article.asp?issn=2148-7731;year=2014;volume=1;issue=2;spage=21;epage=23;aulast=Turan;t=5 DO - 10.4103/2148-7731.132964 N2 - Factor XI (F XI) deficiency is a rare bleeding disorder with an autosomal inheritance and generally asymptomatic. However, the incidence of primary post-partum hemorrhage and secondary post-partum hemorrhage in F XI deficiency were reported as 16% and 24%, respectively. A 35-year-old primigravida woman diagnosed with F XI deficiency was examined by the maternal-fetal medicine service of our hospital at 37 weeks 5 days' gestation. Her blood levels of F XI and activated partial thromboplastin time were %2 and 116 s, respectively at pre-partum period. We made fresh frozen plasma (FFP) replacement 1 day before surgery and we continued transfusions until post-operative 6 th day. The most challenging problems we encountered were hypervolemia and electrolyte imbalance. The management of F XI deficiency necessitates careful consideration and replacement with FFP is believed to be the main approach. ER -