TY - JOUR A1 - Pakkala, Amrith A1 - Bajentri, Ashok A1 - Ganashree, Chitradurga A1 - Raghavendra, Thippeswamy T1 - Hormonal influence on the adaptability of the pulmonary system to exercise in proliferative phase of menstrual cycle in a group of perimenopausal women Y1 - 2014/1/1 JF - Sifa Medical Journal JO - Sifa Med J SP - 2 EP - 4 VL - 1 IS - 1 UR - https://www.imjsu.org/article.asp?issn=2148-7731;year=2014;volume=1;issue=1;spage=2;epage=4;aulast=Pakkala DO - 10.4103/2148-7731.127218 N2 - Background: The role of estrogen on pulmonary function test (PFT) was well-known in the normal course of the menstrual cycle. Significant increase in both progesterone (37%) and estradiol (13.5%), whereas no change in plasma follicle stimulating hormone (FSH) and luteinizing hormone LH was observed in exercising women in previous studies. Therefore, this study was intended to see the limitations of the pulmonary system in adaptability to exercise in proliferative phase of menstrual cycle in perimenopausal women. Materials and Methods: Dynamic lung functions were assessed in two groups of perimenopausal women viz., athletes and non-athletes after treadmill exercise testing using computerized spirometry. Results: It was observed that exercise per se does not cause a statistically significant change in dynamic lung function parameters maximum mid expiratory flow MMEF, peak expiratory flow rate PEFR, and MEF 25-75% in either of the groups. Conclusion: This finding supports the hypothesis that the respiratory system is not normally the most limiting factor in the delivery of oxygen even under the predominant influence of estrogen in proliferative phase which is further accentuated by exercise. ER -