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Year : 2014  |  Volume : 1  |  Issue : 2  |  Page : 21-23

Cesarean section and ovarian cystectomy in the patient with factor XI deficiency

1 Department of Obstetrics and Gynecology, Sifa University Hospital, Izmir, Turkey
2 Department of Hematology, Sifa University Hospital, Izmir, Turkey

Correspondence Address:
Guluzar Arzu Turan
Sanayi Cad No. 7 Bornova, Izmir 35100
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2148-7731.132964

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Factor XI (F XI) deficiency is a rare bleeding disorder with an autosomal inheritance and generally asymptomatic. However, the incidence of primary post-partum hemorrhage and secondary post-partum hemorrhage in F XI deficiency were reported as 16% and 24%, respectively. A 35-year-old primigravida woman diagnosed with F XI deficiency was examined by the maternal-fetal medicine service of our hospital at 37 weeks 5 days' gestation. Her blood levels of F XI and activated partial thromboplastin time were %2 and 116 s, respectively at pre-partum period. We made fresh frozen plasma (FFP) replacement 1 day before surgery and we continued transfusions until post-operative 6 th day. The most challenging problems we encountered were hypervolemia and electrolyte imbalance. The management of F XI deficiency necessitates careful consideration and replacement with FFP is believed to be the main approach.

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