Sifa Medical Journal

REVIEW ARTICLE
Year
: 2016  |  Volume : 3  |  Issue : 2  |  Page : 35--40

Karyotyping: Current perspectives in diagnosis of chromosomal disorders


Suresh Kandagal Veerabhadrappa1, Pramod Redder Chandrappa2, Seema Yadav Roodmal3, Sharan J Shetty4, Gunjiganur S Madhu Shankari2, Kumbar P Mohan Kumar2 
1 Faculty of Dentistry, SEGi University, Petaling Jaya, Selangor, Malaysia
2 Department of Oral Pathology and Microbiology, College of Dental Sciences, Davangere, India
3 Department of Oral Pathology and Microbiology, AJ Institute of Dental Sciences, Mangalore, Karnataka, India
4 Department of Periodontology, Mahatma Gandhi Mission's Dental College and Hospital, Navi Mumbai, Maharashtra, India

Correspondence Address:
Suresh Kandagal Veerabhadrappa
Faculty of Dentistry, SEGi University, No. 9, Jalan Teknologi, Taman Sains, Petaling Jaya, Kota Damansara, Selangor - 47810
Malaysia

A majority of the genetic abnormalities are directly related to the chromosomal aberrations. Cytogenetics is the diagnostic study of the structure and properties of chromosomes and cell division, which employs various methods, one of them being «DQ»karyotyping.«DQ» It refers to a procedure of photographic representation of a stained preparation in which the chromosomes are arranged in a standard manner. The development of newer techniques such as «DQ»karyotyping«DQ» has made it possible to visualize undetected chromosomal anomalies such as small portions of chromosomes and translocations of tiny parts of chromosomes to one another. Because such procedures also enabled each pair of chromosomes to be distinguished individually, it has helped to further our understanding of the chromosomal basis of certain important genetic disorders. This review article highlights the importance of «DQ»karyotyping«DQ» and its importance in the diagnosis of chromosomal disorders.


How to cite this article:
Veerabhadrappa SK, Chandrappa PR, Roodmal SY, Shetty SJ, Madhu Shankari GS, Mohan Kumar KP. Karyotyping: Current perspectives in diagnosis of chromosomal disorders.Sifa Med J 2016;3:35-40


How to cite this URL:
Veerabhadrappa SK, Chandrappa PR, Roodmal SY, Shetty SJ, Madhu Shankari GS, Mohan Kumar KP. Karyotyping: Current perspectives in diagnosis of chromosomal disorders. Sifa Med J [serial online] 2016 [cited 2019 Sep 18 ];3:35-40
Available from: http://www.imjsu.org/article.asp?issn=2148-7731;year=2016;volume=3;issue=2;spage=35;epage=40;aulast=Veerabhadrappa;type=0